Patrick Dempsey and his "Enchanted" co-star Amy Adams. Patrick is seen here at the film's premiere in November of 2007. He has said that he made the film in part because of his daughter, Talula.

We love Patrick and Jillian Dempsey, and it's always nice to see the real-life Mrs. McDreamy out and about with her star husband. They have three children together.

Patrick Dempsey in the movie poster for his 2007-2008 movie "Made of Honor." He's looking very McDreamy as always.

Patrick Dempsey, who plays Derek Shepherd, smiles in a recent interview with Entertainment Tonight. He expressed great concern over the impending Hollywood writers' strike.

Patrick Dempsey takes a stroll through Paris, France - on his own, not as part of a movie scene. Though he looks the part. As always, he's terrific.

Patrick Dempsey out and about in Paris, France. The actor did some sight-seeing, even if it looks as if he's on a movie set!

Patrick Dempsey wearing a towel... not the way some fans might wish, but still, he looks great in this picture.

A portrait of Patrick Dempsey, taken by Entertainment Weekly in October 2007. We love this handsome actor and millions of Grey's Anatomy fans agree.

Patrick Dempsey looks great in pajamas. Are you surprised by this news? We are most definitely not. Great photo, from this week's Entertainment Weekly photo shoot.

Patrick Dempsey enjoys a beverage on the set of a recent photo shoot for Entertainment Weekly. What a handsome fellow. Great picture, too.

Hey, even a handsome actor has to eat. Patrick Dempsey, in his Entertainment Weekly photo shoot in October 2007, looks every bit the McDreamy we are used to seeing.

Contain yourselves, ladies! Patrick Dempsey is seen lying in bed in this Entertainment Weekly photo from October 2007. The handsome Grey's Anatomy star continues to make fans swoon.